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Latest Peer Review Articles By Our Clinical And Medical Team At Global Allied Pharmaceuticals

Immunotherapy And Glioblastoma Multiforme

Download GBM is the most common primary brain tumor. As per the World Health Organization (WHO), GBM is classified as grade IV glioma. GBM is invasive and penetrates the adjoining brain tissue. Incidence is higher in case of men and […]
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IMMUNOTHERAPY AND HEPATOCELLULAR CARCINOMA

Hepatocellular carcinoma (HCC) is considered the most common primary cancer of the liver. HCC accounts for 90% of all liver cancers.HCC is the fifth common cause of cancer in men and seventh in women worldwide. It is the second most […]
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Immunotherapy And Gastroenteropancreatic Neuroendocrine Tumor

Gastroenteropancreatic Neuroendocrine Tumor (GEP-NET) originates from the hormone producing cells of the gut along with rectum and pancreas. GEP-NET represents 75% of all neuroendocrine tumors (NETs). The incidence is 2.5 to 6.2 cases per 100,000 population and 5-year mean survival […]
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IMMUNOTHERAPY AND MALIGNANT PLEURAL MESOTHELIOMA

Malignant pleural mesothelioma is an aggressive type of cancer in which cancerous cells are found in the lining of the abdomen or chest that occurs due to asbestos exposure in the mesothelium. According to the National Cancer Institute’s Surveillance, Epidemiology […]
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IMMUNOTHERAPY AND PANCREATIC CANCER

Integrative Gastroenterology and Hepatology Immunotherapy and Pancreatic Cancer Allen T* , Shoja G and Court NB Global Allied Pharmaceuticals, Center for Excellence in Research and Development, USA * Correspondence: Timothy Allen, Global Allied Pharmaceuticals, Center for Excellence in Research and […]
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IMMUNOTHERAPY AND MENINGIOMA

Immunotherapy and Meningioma Timothy Allen*, Ariel Sheikkhon, Shoja E Razavi, Naveed Basha Court Global Allied Pharmaceuticals, Center for Excellence in Research and Development, USA. timallenmed69@gmail.com *Corresponding Author: Timothy Allen, Global Allied Pharmaceuticals, Center for Excellence in Research and Development, 160 […]
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Immunotherapy And Penis Cancer

Abstract Penis cancer, a cancerous disease in which malignant cells appear in the tissues of the penis. It occurs in the uncircumcised older men. It is recognized by at least two independent carcinogenic routes: virus and non-virus induced. The penis […]
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Competitive Treatment In Diffuse Large B-Cell Lymphoma (DLBCL) And The Future SOC For The First Line Therapy

Download Abstract Diffuse large B-cell lymphoma (DLBCL) in the most common type of non-Hodgkin’s lymphoma (NHL) in developed world, so far and approximately 60,000 new non-Hodgkin lymphoma (NHL) cases and 20,000 deaths have been estimated in the United States for […]
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Frontline Treatment In Diffuse Large B-Cell Lymphoma(DLBCL) And The Futuristic Alternate Standard Of Care For The First Line Therapy

Download Abstract Diffuse large B cell lymphoma (DLBCL) in the most common type of non-Hodgkin’s lymphoma (NHL) in developed world, so far and approximately 60,000 new non-Hodgkin lymphoma (NHL) cases and 20,000 deaths have been estimated in the United States […]
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Malignant Melanoma

Abstract Download Worldwide incidence of malignant melanoma has been constantly increasing during the last years. Surgical excision is effective when primary tumors are thin with thickness of less than 1milli meter and there is no evidence of metastases. At later […]
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Gastrointestinal Events Associated With Ipilimumab And Combination Therapies

Download Gastrointestinal Events Associated with Ipilimumab, Pazopanib, Anti PD1- Antibody and Their Management: Single and Combination Therapies Timothy Allen, MD, Ph.D1*, Giridhar M.N.V, MD,MBA1*, Ghazaleh Shoja E Razavi MD2 1Global Allied Pharmaceutical, Center for Excellence in Research & Development, USA. […]
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PROTEASOME INHIBITION IN LYMPHOPROLIFERATIVE DISORDER.

Abstract Download Proteasomes are multi-subunit protein complexes, which present numerous targets for therapeutic interference. The most commonly used proteasome is 26S proteasome, which contains one 20S proteolytic core subunit and two 19S regulatory cap subunits. There are three different types […]
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Toxicities Associated With Antibody Drug Conjugates

Abstract Download Conventional chemotherapeutic agents, in the treatment of several cancers, lack specificity, resulting in toxicities to normal tissues and poor therapeutic index. Antibody-based immunoconjugates are specifically targeted monoclonal antibodies that deliver the cytotoxic agent to the target cell. When […]
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Mechanisms Of Drug Resistance In Glioblastoma Multiforme.

Abstract Download Glioblastoma multiforme (GBM) is a group of low-grade as well as high-grade brain tumors that originate from the glia;neuroglial cells and are the most common and crucial brain tumor, specially in adults. The main causes are deemed to […]
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A Review On Clinicopathological Correlation Between Classical Inflammatory Bowel Disease And Immunotherapy Related Inflammatory Bowel Disease.

Abstract Download Blockade of various immune targets such as cytotoxic T-lymphocyte antigen-4 and Programmed cell death leads to immune-mediated tumor regression and immune-related adverse events, predominantly gastrointestinal events including diarrhea and colitis. The current review is done to understand the […]
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A Review Of Newer Technologies In Development Of Nanomedicines For Cancers.

Abstract Download Cancer is the leading cause of morbidity and mortality worldwide. Advances in nanotechnology have contributed to the development of nanoparticles used for medical applications and optimized therapy. Due to unique features of nanoparticles, like a large surface area, […]
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Safety And Efficacy Of Peptide Based Vaccines.

Download Abstract A vaccine is a biological preparation which produces immunity from diseases or infections. A vaccine can be administeredby either of the route, orally (through mouth) or through needle injections or by aerosol [1]. Vaccine development process involves induction […]
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Role Of Vascular Endothelial Growth Factor Receptor Inhibitors In Refractory Cervical Cancer.

Download Abstract This review article focuses on the past and future aspects of vascular endothelial growth factor inhibitors in Cervical Cancer.Vascular endothelial growth factor (VEGF)-mediated angiogenesis is considered to play a vital function in the tumor development and metastasis. Therefore, […]
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Immunotherapy In Metastatic Renal Cell Carcinoma.

Download Abstract Immunotherapy plays a crucial role in the treatment of patients with renal cell carcinoma. Metastatic renal cell carcinoma (MRCC) remains a therapeutic challenge because of its strong resistance to both chemotherapy and radiation therapy. This review explains the […]
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Anti-Inflammatory Agents And Their Role In Atherosclerosis.

Download Abstract Atherosclerosis is a chronic disease, with the process of narrowing and hardening of arteries and accumulation of plaques. Normally, atherosclerosis is related with other cardiovascular disease such as peripheral vascular disease, heart attack, and stroke. An inflammation plays […]
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Complementary Medicines And Cancer.

Download Abstract A great strength of patients use complementary medicine, which is an adjuvant to the conventional treatment because complementary medicine is an integrative approach. Conventional treatments have some harmful effects for patients, but many patients use complementary medicine, along […]
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Complementary Medicines And Cancer.

Abstract Download A great strength of patients use complementary medicine, which is an adjuvant to the conventional treatment because complementary medicine is an integrative approach. Conventional treatments have some harmful effects for patients, but many patients use complementary medicine, along […]
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A Review Article On Emerging Role Of Hybrid Molecules In Treatment Of Breast Cancer.

Abstract Download Breast cancer is the most common cancer in women; however, many of them relapse following primary treatment. The pattern of treating breast cancer has been changed over last decades. Dendritic Cell/tumour hybrid, hydroxyphenyltyrosinamide- chlorambucil, SNIPER, hybrid radiopharmaceutical and […]
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A Review On Role Of Peptide Vaccines In Cancer Therapy Treatment Of Cancer Disease By Peptide Vaccine.

Abstract Download The article discuss about the role of peptide vaccine in Cancer therapy. A peptide vaccine is a type of vaccine in which a peptide of the original pathogen is used to immunize an organism. Key words:Vaccines, Angiogenesis, […]
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Growth Factor As A Supportive Treatment In Chemotherapy.

Abstract Download Even after a lot of advancements have been made in the treatment patterns of the various malignancies, there are still a number of dose-limiting toxicities associated with chemotherapy. Most of these toxicities are of hematological nature. Hence, there […]
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Principles Of Nutritional Support In Cancer Patients

Download Abstract Cancer patients are already compromised on nutrition. A good nutrition plays a very important role in cancer patient. Malnutrition delays overall recovery of patient from cancer treatment and may lead to further serious complications. On the other hand, […]
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A Review Article On Neuropathic Pain.

Abstract Download Neuropathic pain is a pathological pain caused due to damaged nerves, as a result of an injury on the somatosensory system. Its effect is mainly on the outside of the brain and spinal cord. Therefore, it is mainly […]
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A Review Article On Clinical Trials On Hybrid Drugs And Nanohybrid Technologies In Drug Development That Combat Cancer. Share

Download Abstract Cancer is one of the highly prevalent diseases worldwide that affects different organs of the body, leading to the rapid and uncontrolled division of cells, forming a mass of tumor cells. There are several conventional therapies available for […]
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Management Of Neurological Adverse Events Associated With Immunotherapy And A Possible Algorithm For Clinical Management.

Abstract Download Different neurological disorders, including alterations of peripheral nerves, multiple sclerosis (MS), optic neuritis (ON), acute transverse myelitis (ATM) and posterior reversible encephalopathy syndrome (PRES) can be associated with some types of immunotherapy. Likewise, anti-tumor necrosis factor alpha (TNF-?) […]
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COX-2 Inhibitors And Their Role In Cancer Prevention And Treatment.

Abstract: Download The various steps in the process of carcinogenesis take many years, which contributes to several opportunities for intervention to inhibit growth of the disease. The reduction in the risk, associated with cancer may be done by few effective […]
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Cancer-Related Fatigue And Its Management.

Download Abstract Fatigue is the most common symptom found in the cancer patients, with a prevalence of more than 60%, as reported in the major part of various studies. This paper mainly reviews the management of the cancer related fatigue. […]
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Cancer-Related Fatigue And Its Management.

Download Abstract Fatigue is the most common symptom found in the cancer patients, with a prevalence of more than 60%, as reported in the major part of various studies. This paper mainly reviews the management of the cancer related fatigue. […]
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Role Of Immunotherapy For H. Pylori In Gastric Cancer.

Download Abstract Gastric cancer is a well-known challenging health problem in the world, which has been deemed to be associated with Helicobacter pylori (H. pylori). H. pylori avoid the endogenous immune reactions. An effective production of antibody against H. pylori […]
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Immunotherapeutic Approach To Squamous Cell Carcinoma Of The Head And Neck.

Download Abstract Head and neck cancers make up of 3-5% of cancer diagnoses in the United States. The most common occur in the squamous cells of the head and neck. Immunotherapy is an alternative to chemotherapy and radiation therapy to […]
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New Targets In Treatment Of Myelodysplastic Syndrome

Download Abstract Myelodysplastic syndrome is a heterogeneous category of hematologic disorders that has been recognized primarily by abnormal morphology and number of blood cells originating from hematopoietic stem cells in the bone marrow based on the genetic as well as […]
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Targeted Therapy For Chondrosarcoma.

Download Abstract Primary malignant bone tumors occur 1/100,000, of which 17-24% consists of chondrosarcoma. Unfortunately, the cause is unknown, but there have been several risks factors accused of causing the disease. Targeted therapy is a cancer specific treatment alternative to […]
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Therapeutic Approach To Chordomas

Download Abstract Chordomas are neoplasms that come from the notochord’s cellular remnants. Immunotherapy is a cancer treatment alternative to chemotherapy and radiation therapy. Its goal is to use a patient’s own immune system to fight the tumor. The immune system […]
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Novel Targets And Breast Cancer Treatment.

Download Abstract Breast cancer is the second most common cancer in women, after skin cancer. One out of every 8 woman in the United States will develop breast cancer. It can be caused by genetic mutations, using certain medicines, or […]
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Novel Approaches In Treatment Of Adult AML

Download Abstract Acute myeloid leukemia (AML) is cancer of the blood cells. This cancer specifically affects red blood cells, platelet forming cells and other white blood cells in the body; its incidence is very low in the United States with […]
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Emerging Role Of Immunotherapy In Breast Cancer.

Download Abstract Breast cancer is the second most common cancer in women, after skin cancer. One out of every 8 woman in the United States will develop breast cancer. It can be caused by genetic mutations, using certain medicines, or […]
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Immunotherapeutic Approach To Osteosarcoma.

Download Abstract Osteosarcoma is a rare form of cancer that account for less than 0.2% of all cancers diagnosed in the United States. Unfortunately, the cause is unknown, but there have been several risks factors accused of causing the disease […]
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Immunotherapeutic Approach To Anal Cancer.

Download Abstract Anal cancer is a rare disease that accounts for 0.4% of all cancer diagnoses in the United States. Its incidence has increased by 2.2% annually. The risk factors associated with anal cancer are Human Papilloma Virus (HPV), Human […]
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